Anthony A. James
| vCard Anthony A. James | |
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| Affiliation: | University of California, Irvine |
| Homepage: | UCI Faculty page |
| Phone: | 949 824-5930 |
| WorkingGroup: | Vectors |
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Anthony A. James, Ph.D. is Distinguished Professor of Microbiology & Molecular Genetics (School of Medicine) and Molecular Biology & Biochemistry (School of Biological Sciences) at the University of California, Irvine (UCI). He is a member of the National Academy of Science (USA) and was a founding editor of the journal, Insect Molecular Biology. He is an Editorial Advisor for PLoS Neglected Tropical Diseases. He received his bachelors of science and PhD degrees at UCI. He went to Boston in 1979 for postdoctoral work (Harvard Medical School and Brandeis University) and joined the faculty at the Harvard School of Public Health in 1985. He returned to his alma mater in 1989, where he is today. Dr. James is working on vector-parasite interactions, mosquito molecular biology, and other problems in insect developmental biology. His research emphasizes the use of genetic and molecular genetic tools to develop synthetic approaches to interrupting malaria parasite and dengue virus transmission by mosquitoes. His research group was the first to develop routine transgenesis procedures for mosquitoes, and they have been able to engineer single-chain antibodies that interfere with malaria parasite development in the mosquito. He is collaborating with other researchers to develop RNAi-mediated approaches to prevent dengue virus transmission. He also is using bioinformatics to study the evolution of control DNA involved in regulating genes involved in hematophagy. He has published over 140 papers, reviews and policy documents and had provided guidance to 34 graduate students and postdoctoral fellows.
