Centruroides sculpturatus

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I5klogo4.jpg Centruroides sculpturatus

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People with a declared interest in Centruroides sculpturatus
Lauren A. Esposito University of California, Berkeley


i5K Comments for Centruroides sculpturatus
Genome size unknown, but Mesobuthus martensii is 600 Mbp. Scorpions are agriculturally important for several reasons. First, they produce venom peptides that specifically target insect nervous systems, and recent research has demonstrated the utility of these peptides as insect biological control agents (Karbat et al., 2004; Song et al., 2011). Secondly, as k-selected, equilibrium species (Polis & Farley, 1980) scorpions have the potential to control insect populations in agricultural regions. Aside from agriculture, scorpions are medically significant. First, they pose a severe public health hazard in Mexico (as well as many other regions of the world) where as many as 250,000 envenomations resulting in up to 2,500 deaths are reported each year. However, scorpions also have therapeutic potential. Their venoms are currently being explored in a variety of treatments including brain gliomas (Kievet et al., 2010) and as analgesics (Wang et al., 2010). All of the medically important venoms come from scorpions in the family Buthidae. Buthids can generally be separated into two groups: the New World buthids and the Old World buthids. Old World buthids produce a family of mammal-specific toxins called beta-toxins, where as New World buthids produce both alpha and beta mammalian toxins. The genus Centruroides is a New World buthid taxon distributed from northern South America to the southern United States, throughout the Caribbean and the Galapagos. The genus is comprised of 71 species, of which 10 are capable of lethal envenomation. A taxonomic revision of this group is currently underway (Esposito, in prep). There are three species of Centruroides naturally distributed in the United States: Centruroides sculpturatus, Centruroides vittatus and Centruroides hentzi. Preliminary results from molecular and morphological analyses indicate that these three species belong to three ecologically, morphologically and genetically divergent clades: Centruroides sculpturatus belongs to a clade of scorpions, endemic to North America, that contains all of the Centruroides species capable of lethal envenomation. In fact, Centruroides sculpturatus has itself been implicated in lethal envenomations of children in the United States. For this reasons, along with the economic and therapeutic potential of buthid scorpion venom peptides, and its natural occurrence in the United States, Centruroides sculpturatus would make an ideal candidate for genome sequencing. (from Lauren Esposito) Jonathan Coddington
Tsunemi Yamashita

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Documents which mention Centruroides sculpturatus


Centruroides sculpturatus
Centruroides sculpturatus
Arizona bark scorpion


Taxonomic classification
Class: Arachnida
Order: Scorpiones
Family: Buthidae
Genus: Centruroides
NCBI taxid: 485px-US-NLM-NCBI-Logo.png 218467
EOL taxid: eol logo grey.png 3195275
Resources
Collection: Baylor i5k pilot
Information
Nomination: i5K initiative
Date: 2011/09/12


I5klogo4.jpg  i5K Arthropod Sequencing Initiative
 Supported by: 3 (List of supporters)



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