The Interactive Fly

The Interactive Fly
Name	Thomas Brody
URL	www.sdbonline.org/fly/aimain/1aahome.htm
Contact	brodyt@ninds.nih.gov
Data_types	Genome data, Gene expression data, Functional genomics data, Comparative genomics data, Literature curation
Resources/Tools	Genome browser

The Interactive Fly stems from thinking about how the information of developmental biology could be held in an easily retrievable form: what is the most efficacious way to portray a non-linear developmental hierarchy of gene activation and repression, characterized by a high degree of complexity? Drosophila melanogaster is an ideal organism for which one can begin with a list of genes active in the egg and follow the morphological changes and gene interactions through to adulthood. Consequently, Drosophila is a good starting place from which to design an interactive model of development. Currently, The Interactive Fly consists of information about 1,100 developmental determinants of Drosophila. Contents include lists of gene by structure and by developmental function. Information about each genes include a biological overview, evolutionary homologs, regulation, protein interaction, expression, and effects of mutation, along with a bibliography.